The cast includes:
Toshiki Seto as Hiiro Kagami/Kamen Rider Brave, a surgeon at Seito University Hospital. Kamen Rider Brave is based on role-playing games.
Ukyo Matsumoto as Taiga Hanaya/Kamen Rider Snipe, a doctor who lost his license and attacks Ho and Kagami. Kamen rider Snipe is based on shooter games.
Ruka Matsuda as Asuna Karino/Poppiipipo Papo
Tetsuya Iwanaga as Kuroto Dan, president of the Genmu corporation
Shojiro Nakazawa is directing the series, while Yuuya Takahashi (Laughing Under the Clouds, Lupin III: Part IV) is credited as head writer. Daichi Miura will perform the series' theme song "EXCITE." The series will celebrate the franchise's 45th anniversary. The series will have visual elements themed after video games, such as gauges seen in fighting games and role-playing games.
The show will premiere on TV Asahi October 2, but the protagonist made an appearance in the Gekijōban Kamen Rider Ghost: 100 no Eyecon to Ghost Unmei no Shunkan (Kamen Rider Ghost The Movie: 100 Eyecons and the Moment of Ghost's Destiny) film, which opened on August 6.